Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. PDF. (When Cookies Enabled), Santaris Pharma A/S is a clinical stage biopharmaceutical company developing next generation RNA-silencing drugs for the treatment of cancer and metabolic diseases. Thanks to their structural characteristics, Spiegelmers are extremely resistant to degradation and not immunogenic a new generation of improved therapeutics. Resistentia Pharmaceuticals ABSwedenDeadpoolResistentia Pharmaceuticals AB, a biotechnology company founded in 1998, developing an allergy vaccine with human as well as veterinary applications. "HIF-1 alpha, as a target, has caught the imagination of the medical community for many years," Orum said. About Antares; Medicines; For Partners; For Investors; For Patients; Careers; Contact Us PDF. LinkedIn We are pleased to announce that Sporos BioDiscovery presented preclinical data on SPR1, a novel TEAD inhibitor program, at EORTC-NCI-AACR Symposium in Barcelona. About Santaris Pharma. If this potential is realised, even in part, it should be possible to design new drugs to treat a wide variety of human diseases by switching off the expression of harmful genes.VentureRadar Research / Company Website. The Company is biology-driven with proprietary technology and a strong focus on product development. Zealand PharmaDenmarkListedZealand Pharma is a biotechnology company focused on the discovery, design and development of innovative peptide-based medicines. These so-called Spiegelmers (the German word Spiegel means mirror) are highly specific for the pharmacologically relevant target for which they were selected. Abstract: The present invention relates to very short heavily modified oligonucleotides which target and inhibit microRNAs in vivo, and their use in medicaments and pharmaceutical compositions. Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted therapies, announced that it has advanced a second drug from its cardiometabolic programme, SPC4955 into phase I clinical trials, for the treatment of high cholesterol. Roche Group Diagnostics pipeline. Resistentia Pharmaceuticals AB, a biotechnology company founded in 1998, developing an allergy vaccine with human as well as veterinary applications. Our pipeline is focused on gastrointestinal, metabolic and other specialty diseases where we believe that the present standard of care is inadequate and where we have the resources to advance our peptide-based product candidates into the later stages of clinical development, including registration and commercialization, while opportunistically considering partnership relationships that may arise. Santaris Pharma 2007 - 2009 2 r. The method may offer new hope to allergy sufferers everywhere because it targets the source of the allergic reaction rather than the symptoms.This is achieved by eliminating IgE, an antibody causing the release of histamine which triggers the allergic reactions for many individuals. Request Profile Update Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. Zealand Pharma is a biotechnology company focused on the discovery, design and development of innovative peptide-based medicines. By using its proprietary Locked Nucleic Acid (:LNA) platform and tissue-targeting expertise, Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or activity of select RNA targets to address diseases which . You can follow this company for updates by clicking here. The report is built using data and information sourced from Global Markets Directs proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Directs team. Swiss Therapeutics company developing therapies to treat severe neurological disorders. Arexis uses forward genetics for a high-resolution molecular dissection of causative disease mechanisms. Santaris' pipeline of RNAi - or ' gene silencing ' - drugs are based on its Locked Nucleic Acid (LNA) platform and its lead candidate is miravirasen, a novel hepatitis C treatment in phase II trials. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis. Such drugs have the potential to transform the field of RNA-targeted therapeutics, making specific and effective gene silencing a reality in human medicine. The core therapeutic focus of our company is obesity, Type II diabetes / metabolic syndrome, inflammatory diseases, and organ protection in severe cardiovascular diseases such as myocardial infarction and post-surgical organ failure. Summary Danish Therapeutics company focused on antibody-drug conjugates (ADCs) for the treatment of cancers. Description Source: VentureRadar Research / Company Website. Santaris Pharma is a biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. Santaris Pharma A/S Advances a Second Drug from Its. Global Markets Directs, Santaris Pharma A/S - Product Pipeline Review - 2014, provides an overview of the Santaris Pharma A/Ss pharmaceutical research and development focus. The top players in pharma know how to adapt. Date of Patent: December 9, 2014. Refresh The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. MedChemComm View Article Online Published on 01 August 2014. We derive our fair valuation of Marina from Roche's August 2014 acquisition of privately held RNAi company Santaris Pharma for $250 million (as well as another $200 million in potential future. Roche (SIX: RO, ROG; OTCQX: RHHBY) has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. Roche has just announced a $450m deal to acquire Danish company Santaris Pharma, a specialist in a form of antisense therapy that switches off a gene by interacting with messenger RNA (mRNA) to. Santaris Pharma A/S - Product Pipeline Review - 2014 is a new market research publication announced by Reportstack. Twitter /PRNewswire/ -- Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted. This new class of medicines has the potential to address difficult to treat diseases in a range of therapeutic areas. The companys research and development activities focus on infectious diseases and cardiometabolic disorders, while partnerships with major pharmaceutical companies include a range of therapeutic areas including cancer, cardiovascular disease, infectious and inflammatory diseases, and rare genetic disorders. [1] The company also had a branch in San Diego, California that opened in 2009. This site 2022 Antares Pharma. features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. WhatsApp acquired by Facebook). Santaris Pharma unveiled its newest microRNA therapeutic program this week having acquired intellectual property from Massachusetts General Hospital related to the use of miR-33 as a target for cardiovascular disorders including hypercholesterolemia. The LNA Drug Platform and Drug Discovery Engine developed by Santaris Pharma A/S combine the companys proprietary LNA chemistry with its highly specialized and targeted drug development. Santaris Pharma A/S was a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. Our R&D activities are focused on applying excellent science to discover and develop potential new medicines with the goal of becoming first-in-class or best-in-class therapeutics. [3] This report provides comprehensive information on the current therapeutic developmental pipeline of Santaris Pharma A/S's, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism . Contact us at the Consulting WP office nearest to you or submit a business inquiry online. Santaris Pharma A/S - Product Pipeline Review - 2014. 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For further information, please contact Santaris Pharma: Dr Keith McCullagh, President & CEO, Santaris Pharma A/S, Copenhagen, Denmark. . It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects. The method may offer new hope Arexis AB, founded by experienced scientists in 1999, is a drug discovery and development company focusing on metabolic and inflammatory diseases. - Santaris Pharma A/S initiates Phase 2a clinical trial with miravirsen (SPC3649) to assess safety and tolerability in treatment-naive patients with chronic Hepatitis C . We are developing two classes of drugs that address gene dysregulation: epigenetic drugs and targeted protein degraders. Santaris, a privately held biopharmaceutical company based near Copenhagen, Denmark, has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. Terms and Conditions Miravirsen is an antimiR developed by Santaris Pharma and was the first drug that targets miRNA, which advanced to clinical trials. These so-called Spiegelmers (the German word Spiegel means mirror) are highly specific for the pharmacologically relevant target for which they were selected. The Company is biology-driven with proprietary technology and a strong focus on product development. CARY, N.C., U.S.A. (March 28, 2022) - Veloxis Pharmaceuticals, Inc., an Asahi Kasei company, today announced initiation of study drug dosing in ART-123.PN101, a phase 1 study designed primarily to assess the safety and tolerability of ART-123 (thrombomodulin . Directory of Companies. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Roche Group Pharmaceuticals pipeline. Santaris Pharma was acquired by Roche in 2014 for $450M. HORSHOLM, Denmark, July 14 -- The Board of Directors of Santaris Pharma has approved the Interim Report for the period 1 January to 30 June 2009. Arexis uses forward genetics for a high-resolution molecular dissection of causative disease mechanisms. HYB_fib (dcRNA) This research strategy is generating a new clinical programme every year and continues to yield novel and proprietary drug targets, key to a more effective development of novel therapies. COPENHAGEN, Denmark | November 10, 2008 | Santaris Pharma announced today that SPC3042, a RNA-based antisense oligonucleotide developed using the company's proprietary Locked Nucleic Acid (LNA) technology, potently blocks survivin, a key survival protein in cancer cells, in both in vitro and in vivo models of prostate cancer. Products on the veterinary market includes the adjuvant for the leading horse influenza vaccine. Eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. As part of its broad patent estate, the company holds exclusive worldwide rights to manufacture, have manufactured and sell products that contain LNA as an active ingredient for studies performed with a view to obtaining marketing approval. By using its proprietary Locked Nucleic Acid (:LNA) platform and tissue-targeting expertise, Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or . Commun., 2014, 5, 1454 Vivek K. Sharma,a Raman K. Sharmab and Sunil K. Singh*c There has been an upsurge in the number of clinical trials . The method may offer new hope to allergy sufferers everywhere because it targets the source of the allergic reaction rather than the symptoms.This is achieved by eliminating IgE, an antibody causing the release of histamine which triggers the allergic reactions for many individuals. Yesterday, Roche paid $250m - plus a potential $200m more in milestone payments - to buy Copenhagen, Denmark-based biotech Santaris (owned in part by private equity firms Forbion Capital Partners and Seventure Partners) in a deal that adds three RNA-targeted therapies to its pipeline as well as the proprietary microRNA Locked Nucleic Acid . The vaccine would be safer, easier to administer and more cost effective than other potential drug candidates currently under development. Contact Us Downloaded by University of Colorado at Boulder on 06/07/2015 23:37:18. REVIEW View Journal | View Issue Antisense oligonucleotides: modications and clinical trials Cite this: Med. in addition to miravirsen, santaris pharma a/s has a robust product pipeline targeting mrnas and micrornas both internally as well as in partnerships and collaborations with miragen therapeutics (cardiovascular diseases), shire plc (rare genetic disorders), pfizer (undisclosed therapeutic areas), glaxosmithkline (viral disease) and enzon It is designed to target the viral mRNA and therefore provides for low off-target effects. US-based Healthtech company providing remote patient monitoring solutions for COPD patients. Cookie Policy Action Pharma A/S is a clinical stage biopharmaceutical company founded in 2000 and located in Denmark with offices and laboratories in Aarhus and Copenhagen. [1] The company also had a branch in San Diego, California that opened in 2009. Acute & chronic kidney injury We focus on a very specific protein (undisclosed) that plays a major role in inflammation / fibrosis. Santaris Pharma A/S, founded in 2003, is headquartered in Denmark with operations in the United States. santaris pharma a/s has a robust product pipeline based on its proprietary lna technology including mrna and microrna drug discovery and development partnerships and collaborations with shire (rare genetic disorders), wyeth, now part of pfizer, (delivery of lead candidates against up to ten targets), glaxosmithkline (four viral disease drug Vaccines for veterinary and human use. Veloxis Pharmaceuticals, Inc. Initiates Phase 1 Study of ART-123 in the U.S. and Japan. Active, Closed, Last funding round type (e.g. Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam. Zealand Pharma is a biotechnology company focused on the discovery, design and development of innovative peptide-based medicines. IsconovaSwedenAcquiredVaccines for veterinary and human use. Since Gilde invested in Santaris Pharma, the company has advanced its product pipeline through the clinic and signed commercial collaboration agreements with GlaxoSmithKline, Pfizer, Bristol-Myers Squibb, Roche and Shire. Santaris Pharma was acquired by Roche in 2014 for $450M. Thanks to their structural characteristics, Spiegelmers are extremely resistant to degradation and not immunogenic a new generation of improved therapeutics. Our pipeline is focused on gastrointestinal, metabolic and other specialty diseases where we believe that the present standard of care is inadequate and where we have the resources to advance our peptide-based product candidates into the later stages of clinical development, including registration and commercialization, while opportunistically considering partnership relationships that may arise. Santaris Pharma A/Swas a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. NOXXON PharmaGermanyListedNOXXON Pharma AG (Berlin, Germany) based on one of the biggest and best protected patent portfolios in the industry, Berlin-based NOXXON Pharma AG develops biostable aptamers, novel substances based on mirror image nucleic acids. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products. Privacy Policy The Roche Innovation Center in Copenhagen, originating from the acquisition of Santaris Pharma in 2014, is a leader in the rapidly emerging field of RNA-targeted drugs. Arexis ABSwedenAcquiredArexis AB, founded by experienced scientists in 1999, is a drug discovery and development company focusing on metabolic and inflammatory diseases. Santaris Pharma is a Company located in Denmark, Europe, and was founded in 2003. This report provides comprehensive information on the current therapeutic developmental pipeline of Santaris Pharma A/Ss, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. Edit Lists Featuring This Company Section, Specialty Active Pharmaceutical Ingredients (API) Market: Global Industry Analysis and Opportunity Assessment, 2016 - 2024, Ophthalmic Drugs Market Forecast 2016-2026, Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2016-2026, European Union (EU) Companies that Exited (Top 10K), Closed European Union (EU) Health Care Companies. Santaris Pharma: Company in Denmark, Europe. This report provides comprehensive information on the current therapeutic developmental pipeline of Santaris Pharma A/Ss, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The popularity score combines profile views, clicks and the number of times the company appears in search results. You must have cookies enabled to login Continue reading on Roche.com: Locked Nucleic Acid (LNA) Platform. Santaris Pharma AS - Pharmaceuticals & Healthcare - Deals and Alliances Profile Published by GlobalData at researchbeam.com [Report Price $250] 29 Pages help@researchbeam.com +1-971-202-1575 | Toll Free: +1 (800)910-6452 Investors eagerly await updates on the pipelines of pharma/biotech companies. Formerly known as SPC2968, the drug now called RG6061 was previously under development with Enzon Pharmaceuticals, but Santaris regained full ownership of the compound last year when that partnership ended. Santaris Pharma is developing a diverse pipeline of LNA therapeutics that influence the production or activity of select RNA targets to address diseases that are difficult-to-treat with . Santaris Pharma A/S - Product Pipeline Review - 2014 is a new market research publication announced by Reportstack. - The report provides brief overview of Santaris Pharma A/S including business description, key information and facts, and its locations and subsidiaries, - The report reviews current pipeline of Santaris Pharma A/Ss human therapeutic division and enlists all their major and minor projects, - The report features product description and descriptive mechanism of action for key pipeline products along with the products developmental history and major milestones, - Special feature on out-licensed and partnered product portfolio, - The report summarizes all the dormant and discontinued pipeline projects, - Latest news and deals relating to the Santaris Pharma A/Ss pipeline products, - Evaluate Santaris Pharma A/Ss strategic position with total access to detailed information on its product pipeline, - Assess the growth potential of Santaris Pharma A/S in its therapy areas of focus, - Identify new drug targets and therapeutic classes in the Santaris Pharma A/Ss R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas, - Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps, - Develop strategic initiatives by understanding the focus areas of Santaris Pharma A/S and exploit collaboration and partnership opportunities, - Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage, - Plan mergers and acquisitions effectively by identifying the most promising pipeline of Santaris Pharma A/S, - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope, - Explore the dormant and discontinued projects of Santaris Pharma A/S and identify potential opportunities in those areas, - Avoid Intellectual Property Rights related issues, Pharma Pipeline Review - Market Research Reports, Santaris Pharma A/S - Product Pipeline Review - 2014. 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